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Urethral obstruction may cause excessive bladder distension resulting in detrusor atony or weakness, which disrupts tight junctions between muscle cells. This is common in cats with。

If reflex of the detrusor exists and but it is insufficient to induce a suitable evacuation, it is possible to stimulate the contraction of the bladderdetrusor atony cat using some Prokinetics as the Cisapride (dogs 0.1-0.5 mg/kg c/8-12 hrs. and cats 2.5-5 mg。

Detrusor atony is a condition that occurs in previously obstructed cats after excessive expansion of the urinary bladder.19 In this condition, the tight junctions of the smooth muscle in the bladder become stretched or torn apart,。

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